Michael Stolt

PDF The BioBreeding rat diabetes model is infected with

The initial findings were made among bank voles, which are the most common mammal in Scandinavia. The Ljungan virus was later discovered in several animal species causing diseases such as diabetes, perinatal death and malformations in several animal species. Ljungan virus, first described in 1998, has been the subject of recent interest because of its apparent role in the pathogenesis of type 1 diabetes in rodents and because of a possible emerging role in human disease (Tolf et al., 2009). 2015-10-08 Ljungan virus (LV) was discovered 20 years ago in Swedish bank voles (Myodes glareolus, previously referred to as Clethrionomys glareolus) during the search for an infectious agent causing lethal myocarditis in young athletes. To date, the genomes of four LV isolates, including the prototype 87-012 strain, have been characterized.

Simple Ljungan virus är ett nyupptäckt virus och därför är kunskapen om viruset begränsad. För att öka vår förståelse om viruset så har arvsmassan för tre svenska isolat (87-012, 174F och 145SL) av Ljungan virus kartlagts (artikel IV). Denna studie visade att Ljungan virusets arvmassa har flera unika egenskaper. Ljungan virus cDNA. The Ljungan virus isolate 87-012 (23) was subcloned in the pCRII- TOPO vector (Life technologies, Grand Island, NY) to contain nucleotide posi-tions 301–2685 representing VP0 (VP2), VP3, and VP1(28). The resulting cDNA clone, pLV1, was veriﬁed by sequencing and used in coupled in vitro transcription translation to label Ljungan virus Download PDF Info Publication number US20110300149A1.

Översvämningar i Polen 1997 och i Sverige 2000

– p 692-702 . Abstract: In addition to the viruses belonging to the nine proposed genera of the Picornaviridae, Enterovirus, Rhinovirus, Cardiovirus, Aphtovirus, 22 Oct 2015 Key words: Parechovirus B, picornaviruses, rodent-borne viruses, virology, zoonoses.

Oförklarligt dödfödda spädbarn bar på Ljunganvirus

The genus currently consists of six accepted species. Human parechoviruses may cause gastrointestinal or respiratory illness in infants, and have been implicated in cases of myocarditis and encephalitis. Read "Ljungan virus: A commentary on its association with fetal and infant morbidity and mortality in animals and humans, Birth Defects Research Part A" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Ljungan virus a novel pathogen : Effects on the pregnant female and her offspring Relationship Between Ljungan Virus Antibodies, HLA-DQ8, and Insulin Autoantibodies in Newly Diagnosed Type 1 Diabetes Children. Research output: Contribution to journal › Article In four of these Ljungan virus was found in the stillborn children as well.

Ljungan (Jamtlandic: Jångna or Aoa, from Old Norse *Oghn "the dreadful") is a 322 kilometer long river in Sweden. It originates near Trondheim and the Norwegian border. The river runs through the Swedish counties of Jämtland and Västernorrland .
Medicinsk grundkurs bok

Cover image for Geographical Distribution of Ljungan Virus in Small Mammals in Europe. Scientific publication av B Andersson — Nyligen har ett nytt virus isolerats från sork infångad vid floden Ljungan i Medelpad varför virus benämns Ljunganvirus. Detta virus tillhör liksom enterovirus Sammanfattning: Ljungan virus (LV) is a recently identified picornavirus of the genus Parechovirus. LV has been isolated from voles trapped in Sweden and also [Irrelevant about Ljungan. virus] · Tomas Bergström, Jan-Åke Liljeqvist Läkartidningen - 2009-01-01.

Several scientific articles have recently reported findings indicating that Parechovirus B is associated with malformations, intrauterine fetal deat Structure of Ljungan virus provides insight into genome packaging of this picornavirus Abstract. Picornaviruses are responsible for a range of human and animal diseases, but how their RNA genome is packaged Introduction. Encapsidation of the viral genome leading to the assembly of infectious Ljungan virus (LV) was discovered 20 years ago in Swedish bank voles (Myodes glareolus, previously referred to as Clethrionomys glareolus) during the search for an infectious agent causing lethal myocarditis in young athletes. To date, the genomes of four LV isolates, including the prototype 87-012 strain, have been characterized. Ljungan virus is a picornavirus isolated from Swedish and North American rodents. Replication of Ljungan virus in cultured cells normally induces a weak and delayed cytopathic effect compared to that of many other picornaviruses.
Chokladfabriken cloetta

2. Samsoe A, Papadogiannakis N, Hultman T, Sjöholm A, Klitz W, Niklasson B. Ljungan virus present in intrauterine fetal death diagnosed by both immunohisto-chemistry and PCR. Birth Defects Ljungan virus is a recently identified member of the family Picornaviridae that was isolated from bank voles in Sweden. It has been shown to cause type 1 diabetes-like symptoms and myocarditis in bank voles (Myodes glareolus), and it has been suggested that it has zoonotic potential. Here, we show for the first time that Ljungan virus is prevalent (20–27 % positive by PCR) in four Ljungan virus är ett virus som isolerades i Sverige i mitten på nittiotalet. Under perioden 1989-1992 avled flera svenska elitorienterare plötsligt i hjärtmuskelinflammation.

- The Ljungan virus’ so called “2A gene” is doubled, which means that its gene pool is organised in a way that … Relationship Between Ljungan Virus Antibodies, HLA-DQ8, and Insulin Autoantibodies in Newly Diagnosed Type 1 Diabetes Children Anna-Lena Nilsson,1,2 Fariba Vaziri-Sani,2 Cecilia Andersson,2 Karin Larsson,3 Anneli Carlsson,2 Elisabeth Cedervall,4 Bjo¨rn Jo¨nsson,5 Jan Neiderud,6 Helena Elding Larsson,2 Sten-Anders Ivarsson,2 and A˚ke Lernmark2 Abstract Molecular characterization of a novel Ljungan virus (Parechovirus; Picornaviridae) reveals a fourth genotype and indicates ancestral recombination. J Gen Virol.
Lediga arbeten ica

gdpr trader i kraft
nakd allabolag
lfv flygledare
allmän pension engelska
vilket län ligger göteborg i
richard walters spencer fane
barn bathroom mirror

Översvämningar i Polen 1997 och i Sverige 2000

In BB rats LV was found in both prediabetic- and diabetic DPBB … Relationship Between Ljungan Virus Antibodies, HLA-DQ8, and Insulin Autoantibodies in Newly Diagnosed Type 1 Diabetes Children Anna-Lena Nilsson,1,2 Fariba Vaziri-Sani,2 Cecilia Andersson,2 Karin Larsson,3 Anneli Carlsson,2 Elisabeth Cedervall,4 Bjo¨rn Jo¨nsson,5 Jan Neiderud,6 Helena Elding Larsson,2 Sten-Anders Ivarsson,2 and A˚ke Lernmark2 Abstract Ljungan virus (LV), which belongs to the Parechovirus genus in the Picornaviridae family, was first isolated from bank voles (Myodes glareolus) in Sweden in 1998 and proposed as a zoonotic agent.To improve knowledge of the host association and geographical distribution of LV, tissues from 1685 animals belonging to multiple rodent and insectivore species from 12 European countries were … Molecular characterization of a novel Ljungan virus (Parechovirus; Picornaviridae) reveals a fourth genotype and indicates ancestral recombination. J Gen Virol. 90: 843-653. Epub 2009 Mar 4.